Analysis of Metabolite Levels, Secondary Minerals and Aloe Vera Formulation from Kalimantan Indonesia
DOI:
https://doi.org/10.31964/mltj.v0i0.417Keywords:
Aloe vera, secondary metabolites, mineral levels, gel, teethAbstract
Products from natural ingredients such as aloe vera must be high quality and meet standardization aspects. Determination of secondary metabolites and mineral levels is part of the standardization of natural product products. The dosage formula needs to be optimized to get the best formula based on evaluating the physical properties of the gel preparation. This study aimed to analyze the highest mineral and metabolite content between aloe vera from South Kalimantan and West Kalimantan, as well as the optimum formula for aloe vera gel based on its physical properties. The research method used is to perform sample preparation, extraction, analysis of minerals and secondary metabolites by spectroscopy. The data were analyzed descriptively, and the results showed that the content of iron, calcium, and zinc originating from West Kalimantan was 0.314 mg/g; 93.42 mg/g; 0.059 mg/g, while South Kalimantan 0.064 mg/g, 53.24 mg/g, 0.032 mg/g. The total phenolic, flavonoid, and anthraquinone levels from West Kalimantan were 0.512%, 1.31%, respectively, 2.28%, while those from South Kalimantan were 0.321%, 1.12%, 1.14%. The best formula for aloe vera gel is formula three, which has a darker color and meets the requirements of the physical properties of the gel. This study concludes that the highest mineral content in aloe vera comes from West Kalimantan, the highest secondary metabolite content also comes from West Kalimantan. And the best formula is the third formula with 20% natural dyes. Suggestions for further research are to examine the mineral content and secondary metabolites of aloe vera in various places in Indonesia so that the best aloe vera can be known.References
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Astuti, E., Sunarminingsih, R., Jenie, U., Mubarika, S., Sismindari. (2014). Pengaruh lokasi tumbuh, umur tanaman dan variasi jenis destilasi terhadap komposisi senyawa minyak atsiri rimpang curcuma mangga produksi beberapa sentra di Yogyakarta. J. Manusia Dan Lingkungan, 21(3), 323-330
Buulolo, A. & Syamsul, D. (2016). Formulasi sediaan gel sari lidah buaya (aloe vera l.) Sebagai sebagai obat luka. Jurnal Dunia Farmasi, 1(1)
Chowdhury, T. Rahman, M. Nahar, K. Chowdhury, A. Khan, S (2018). Growth and yield performance of Aloe vera grown in different soil types of Bangladesh. J Bangladesh Agril Univ, 16(3), 448–456
Fasoulas A, Pavlidou E, Petridis D, Mantzorou M, Seroglou K, Giaginis C. (2019). Detection of dental plaque with disclosing agents in the context of preventive oral hygiene training programs. Heliyon, 5(1)
Garg, A., Aggarwal, D., Garg, S., & Singla, A. K. (2002). Spreading of semisolid formulations: an update. Pharmaceutical Technology North America, 26(9), 84-84.
Istanto, N. (2014). Respon pertumbuhan lidah buaya (Aloe vera) terhadap pemberian kalium dan tandan kosong kelapa sawit (TKKS). Skripsi. Prodi Agroekoteknologi, Fakultas Pertanian, Universitas Bengkulu.
Kurnianingsih, A. (2004). Tanggap tanaman lidah buaya (Aloe vera Chinensis) terhadap pemberian mikroba dan abu janjang kelapa sawit di lahan gambut. Tesis Magister Sains. Sekolah Pascasarjana
Lopez, A. Tangil, M. Vega-Orellana, O. Ramirez, A. Rico, M. (2013). Phenolic constituents, antioxidant and preliminary antimycoplasmic activities of leaf skin and flowers of aloe vera (l.) Burm. F. (syn. A. Barbadensis mill.) From the Canary Islands (Spain). Molecules,18(3), 4942-4954
Marhaeni, L. (2020). Potensi lidah buaya (aloe vera linn) sebagai obat dan sumber pangan. Agrısıa-Jurnal Ilmu-Ilmu Pertanian, 13(2), 32-39.
Miladi, S., & Damak, M. (2008). In vitro antioxidant activities of aloe vera leaf skin extracts. J Soc Chim Tunisie, 10(10), 101-109
Mulyanita, M., & Setiasih, I. S. (2019). Total fenol, flavonoid dan aktivitas antimikroba ekstrak limbah kulit lidah buaya (Aloe chinensis Baker). Jurnal Vokasi Kesehatan, 5(2): 95-102
Mutiara. (2007). Pengaruh komposisi pelarut pada pembuatan ekstrak daun lidah buaya (Aloe vera L.) dengan parameter kadar antrakinon total dihitung sebagai Aloin. Tesis. Pascasarjana Ilmu Farmasi UGM
Nevi, S. (2006), Formulasi sabun transparan minyak nilam sebagai obat jerawat. Skripsi. FMIPA Universitas Muhamadiyah. Surakarta
Pawar, S. & Kamble, V. (2013). Quantitative assessment of mineral composition of Aloe vera (L.) Burm.f. leaves by ICP-MS and CHNS analyzer. International Journal of Science and Research (IJSR), 4(10)
Purbaningtyas, E. Yuliani, F. Ananda, A. Sari, R. (2020). Disclosing agent from red dragon fruit peel as dental plaque indicator. Odonto Dental Journal, 7(1)
Rajendran, A., Narayanan, V., Gnanavel, I. (2007). Study on the analysis of trace elements in aloe vera and its biological importance. Journal of Applied Sciences Research, 3(11), 1476-1478
Rizki, M. (2020). Farmakognosi dan Metabolit Sekunder. Penerbit CV. IRDH. Malang
Rizki, M. (2021). Review: Fitoterapi pada keadaan anemia. Journal Current Pharmaceutical Sciences, 5(1)
Rizki M, Nurlely N, Fadlilaturrahmah, Mashumah. (2021). Skrining fitokimia dan penetapan kadar fenol total pada ekstrak daun nangka (artocarpus heterophyllus), cempedak (artocarpus integer), dan tarap (artocarpus odoratissimus) asal desa Pengaron kabupaten Banjar. Jurnal Insan Farmasi Indonesia, 4(1), 95-102
Suryani, N. Mubarika, D. Komala, S. (2019). Pengembangan dan evaluasi stabilitas formulasi gel yang mengandung etil p-metoksisinamat. Pharmaceutical and Biomedical Sciences Journal, 1(1), 29-36
Tranggono, R. I., & Latifah, F. (2007). Buku pegangan ilmu pengetahuan kosmetik. Jakarta: PT. Gramedia Pustaka Utama.
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Published
2022-06-27
How to Cite
Said, F., Rahmawati, I., & Ningsih, N. S. (2022). Analysis of Metabolite Levels, Secondary Minerals and Aloe Vera Formulation from Kalimantan Indonesia. Medical Laboratory Technology Journal, 8(1), 27–34. https://doi.org/10.31964/mltj.v0i0.417
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